The role of inositol supplementation in patients with polycystic ovary syndrome, with insulin resistance, undergoing the low-dose gonadotropin ovulation induction regimen

The role of inositol supplementation in patients with polycystic ovary syndrome, with insulin resistance, undergoing the
low-dose gonadotropin ovulation induction regimen

In an attempt to evaluate the role of inositol supplementation in insulin-resistant patients with polycystic ovary
syndrome (PCOS), undergoing gonadotropin ovulation induction using the low-dose step-down regimen, we
conducted a prospective longitudinal study comparing the stimulation characteristics of 15 patients treated with
inositol, to a cohort, matched by age and body mass index (BMI), without inositol. Inositol nutritional supplementation
produced very good clinical results with a significant reduction in cancellation rate (0 vs. 40%) and the consequent
improvement in clinical pregnancy rate (PR) (33.3% vs. 13.3%). (Fertil Steril 2011;-:-–-. 2011 by
American Society for Reproductive Medicine.)

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